Update in Thymoma for Surgical Pathologists
Thymoma is the most common mediastinal tumor in adulthood. By definition, it is a thymic epithelial neoplasm that displays at least some characteristics of normal thymus. Microscopically it comprises an admixture of thymic epithelial cells and immature T lymphocytes in various proportions and demonstrates marked intratumoral heterogeneity...
Is immunohistochemistry mandatory in staging bone marrow trephine biopsy of patients with diffuse large B-cell lymphoma (DLBCL)
Diffuse large B-cell lymphoma (DLBCL) can be found involving bone marrow in approximately 11-27% of cases 1. Patterns of involvement are variable; these include diffuse pattern (lymphomatous cells diffusely infiltrating the marrow), interstitial pattern (i.e. small amount of lymphomatous cells scattered among hematopoietic cells), nodular pattern (lymphomatous cells forming aggregates in intertrabecular or paratrabecular area of the marrow).. ...
Update in Thymoma for Surgical Pathologists
Thymoma is the most common mediastinal tumor in adulthood. By defi nition, it is a thymic epithelial neoplasm that displays at least some characteristics of normal thymus. Microscopically it comprises an admixture of thymic epithelial cells and immature T lymphocytes in various proportions and demonstrates marked intratumoral...
A practical approach to undifferentiated tumors: A review on helpful markers and common pitfalls
The term “undifferentiated” tumor is commonly used by pathologists when a tumor lacking evidence of lineage differentiation on the basis of routine light microscopic morphology is encountered. Immunohisto- chemistry plays an important role in elucidating the true nature of the undifferentiated tumor that is crucial for clinical management....
